FASPRIN® - CLINICAL STUDIES SUPPORTING USE
FASPRIN “WOMEN’S HEART HEALTH”
The following studies support the need for women to take low dosage aspirin daily. Less than 15% of women in the high risk segment use daily aspirin therapy.
Women Need to use Low Dose Aspirin every day
The bottom line is that many women, especially those 65 and older, may benefit from taking low-dose aspirin every other day to prevent stroke. The greatest benefit appeared to be in women 65 and older. In this sub-group, low-dose aspirin reduced the risk of major cardiovascular events by 26 percent. Statement from Elizabeth G. Nabel, M.D., Director of the National Heart, Lung, and Blood Institute of the National Institutes of Health on the Findings of the Women’s Health Study (10 year study 40,000 participants in 2005)
Women are four times more likely than men to develop clot’s
Women were found to have clotting four times more likely than in men. In what is believed to be the first direct comparison of blood plasma testing in both sexes after taking 81 milligrams of aspirin a day. Hopkins researchers found aspirin therapy prevents the clumping together of platelets, the clot-forming cells. Clots in blood vessels of the heart and brain can cause heart attacks and strokes. Hopkins Study Shows Low-Dose Aspirin Suppresses Clumping Of Blood Platelets In Both Sexes (More than 500 men and 700 women participated in the study, called the Genetic Study of Aspirin Responsiveness in 2005)
FASPIRIN FOR GENERAL HEART HEALTH
Daily use of low dose aspirin could reduce the risk of a cardiac event for over 100 million people according to the American Heart Association.
Low dose aspirin aids prevention of cardiovascular and cerebrovascular events
Aspirin is the most widely used and most studied therapy in the history of medicine. High doses alleviate pain and inflammation, moderate doses for short term management of acute pain and low doses for cardiovascular and cerebrovascular disease prevention. Low dose aspirin (less than 325 mg) reduced heart attacks by 30%, strokes by 20%, and other vascular events by 30%. In six trials (6300 patients) there were no cases of GI bleeding that were fatal. Aspirin reduced all-cause mortality by 18%.Archives of Internal Medicine 2002:162:2197-2202
Low dose aspirin reduces the risk of major cardiovascular event
The researchers found that patients who took low-dose aspirin had a 26 percent reduction in the risk of a nonfatal heart attack, a 25 percent reduction in the risk of stroke and a 13 percent reduction in risk of death, compared with similar heart patients who did not take aspirin. Taken together, Berger said, patients on low-dose aspirin had a 21 percent reduction in risk of experiencing a major cardiovascular event, a measurement that is the combination of the rates of nonfatal heart attack and stroke and of cardiovascular death. Aspirin for cardiovascular disease prevention, Joseph Hung, for the Medical Issues Committee of the National Heart Foundation of Australia
CDC Promotes low dose aspirin use.
A simple aspirin is one of the cheapest and most widely available therapies for preventing life-threatening complications of diabetes, yet few people are taking advantage of it, according to researchers at the CDC in Atlanta.
FASPRIN HELPS REDUCE GASTRIC RISK
Fasprin dissolves in the mouth rapidly entering the blood stream. It is not absorbed in the stomach or intestine.
Low-dose aspirin is best choice for cutting bleeding risks
A survey of 8 studies demonstrated a non-significant increase in esophageal, gastric and duodenal ulcers during treatment with low dose aspirin, but noted GI bleeding in 3% of cases. Gastric erosions are more frequent in the elderly than in younger subjects. Presse Med. 2003 Nov 22;32(37 Pt 2):S17-28.
Even Low Dose of Aspirin Can Cause Intestinal Bleeding
While the risk of bleeding associated with long-term aspirin use has been widely recognized, it now appears that even fairly low doses -- which some people may have considered safe -- increases the risk, say Yoon Kong Loke, MBBS, and Sheena Derry, MBBS, of the department of clinical pharmacology at the University of Oxford in England.
FASPRIN ADDRESS THE PROBLEMS WITH ENTRIC COATED ASPRIN
Study has shown that enteric coated aspirin does not provide the cardioprotective benefits of platelet inhibition with over 50% of patients in two major studies.
Low-dose coated aspirin inadequate
Many patients taking daily low-dose enteric-coated aspirin to prevent cardiovascular events show incomplete platelet inhibition, reported Andrew O. Maree, M.D., of the Royal College of Surgeons, Dublin, and his associates. In a study involving healthy volunteers, Dr. Maree and his associates found that enteric-coated aspirin was less effective. COPYRIGHT 2005 International Medical News Group
Baby aspirin, coated aspirin may not prevent stroke
A study involving 250 persons showed that 50% who took coated or 81 mg. low-dose “baby” aspirin had normal platelet function, or half of the patients had no protection against heart attacks or stroke. Those taking 325 mg aspirin, 72% had measurable effects indicating decreased platelet function or cardioprotection.Alberts M, American Stroke Assn, Phoenix Arizona, February 14, 2003.
FASPRIN WORKS FASTEST IN AN EMERGENCY
Fasprin is five time faster than regular coated low dose aspirin. Fasprin enters the blood steam in 3 to 5 minutes, where enteric coated aspirin take over 40 minutes and regular aspirin take 20 to 30 minutes.
Time is important in treating heart attacks
Each year 1.5 million Americans suffer heart attacks, and 1/3 die of that first attack, one half being females. Most of the 500,000 deaths occur within 2 hours after chest pain or other symptoms. In Britain, half of all heart attack patients die within 2 hours of symptom onset and 2/3rds of the deaths occur before hospital admission.Pre-Hospital Immediate Care 1997;1:12-18.
Aspirin used be taken at first signs of cardiac event
Aspirin has been considered to be very important in initial treatment of people who are having heart attacks. We know that people who use aspirin can reduce their risk of dying from their heart attack by about 30 percent. DAVID F. KONG, MD:
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